A man is dying of heart failure. He has a heart disease with no cure. His wife decided to have him cryogenically frozen, to be thawed only when the cure for the disease is available. The wife, with her love and devotion, also asked to be cryogenically frozen herself, to be thawed when his husband is cured.
The cure was developed 500 years later. The man and his wife was thawed. They went to see each other. But as they met, they have become very far apart. There was no more warmth and affection, no more love and devotion. So they consulted the doctors about it.
The doctors have no solid explanation but they have a theory. They think the couple have been frozen for too long. Their hearts have grown cold.